Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29562727 | 0.97 | THRB (0.59) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL9769220 | 0.97 | THRB (0.59) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL9494057 | 0.97 | THRB (0.59) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3390334 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3383150 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL11802800 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3383145 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3390329 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL10598950 | 0.94 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL11123018 | 0.82 | THRB (0.83) | THRBMEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737209-B1 | METAL ION-LIGAND COORDINATION COMPLEXES, ANTIBODIES DIRECTED THERETO, AND ASSAYS USING SUCH ANTIBODIES | ABBOTT LAB (US) | 2003-09-03 | — | — | EP | disclosed |
| US-5683907-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-11-04 | — | — | US | disclosed |
| US-5681960-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-10-28 | — | — | US | disclosed |
| US-5670627-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5670645-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |
| US-5663301-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5654160-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-08-05 | — | — | US | disclosed |
| US-5631172-A | Metal ion-ligand coordination complexes, antibodies directed thereto, and assays using such antibodies | ABBOTT LABORATORIES (US) | 1997-05-20 | — | — | US | disclosed |
| US-5476939-A | Certain pyridyl and isoquinolyl carbinolamine derivatives | ABBOTT LABORATORIES (US) | 1995-12-19 | — | — | US | disclosed |
| US-5053226-A | Cell line resulting from fusion of neoplastic cell with cell from animal immunized against compley | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-10-01 | — | — | US | disclosed |
| WO-1990012109-A1 | MONOCLONAL ANTIBODIES BINDING PLATINUM COMPLEXES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-10-18 | — | — | WO | disclosed |