Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29562727 | 1.00 | THRB (0.59) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL9494057 | 1.00 | THRB (0.59) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL7095699 | 0.97 | THRB (0.56) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3390334 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3390329 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL10598950 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL11802800 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3383145 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| Sulfuric Acid SCHEMBL3383150 | 0.97 | THRB (0.62) | THRBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL31514393 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2286694-A | — | — | None | — | — | JP | disclosed |
| JP-2311489-A | — | — | None | — | — | JP | disclosed |
| JP-2042094-A | — | — | None | — | — | JP | disclosed |
| JP-3011091-A | — | — | None | — | — | JP | disclosed |
| JP-3011090-A | — | — | None | — | — | JP | disclosed |
| JP-H0311090-A | NOVEL PLATINUM-CONTAINING COMPOUND AND REMEDY FOR MALIGNANT TUMOR | TORAY IND INC | 1991-01-18 | — | — | JP | disclosed |
| JP-H0311091-A | NOVEL PLATINUM (II) COMPLEX AND REMEDY FOR MALIGNANT TUMOR | TORAY IND INC | 1991-01-18 | — | — | JP | disclosed |
| JP-H02311489-A | NEW PLATINUM-CONTAINING COMPOUND AND TREATING AGENT FOR MALIGNANT TUMOR | TORAY IND INC | 1990-12-27 | — | — | JP | disclosed |
| JP-H02286694-A | NEW PLATINUM (II) COMPLEX AND MALIGNANT TUMOR REMEDY | TORAY IND INC | 1990-11-26 | — | — | JP | disclosed |
| US-4912100-A | Containing cyclohexanediamine and tetrahydropyran rings | TORAY INDUSTRIES, INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4870062-A | REDUCED NEPHROTOXICITY | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0288002-A2 | Organo-platinum complex and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1988-10-26 | — | — | EP | disclosed |
| EP-0264109-A1 | Platinum complex, process for preparing same and antitumor agent | TORAY INDUSTRIES, INC. (JP) | 1988-04-20 | — | — | EP | disclosed |
| EP-0112591-B1 | NOVEL GLYCOLIC ACID PLATINUM COMPLEXES | SHIONOGI & CO., LTD. (JP) | 1986-06-11 | — | — | EP | disclosed |
| US-4577038-A | ANTITUMOR | SHIONOGI & CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4575550-A | ANTITUMOR AGENTS WITH LESS NEPHROTOXICITY | SHIONOGI & CO., LTD. (JP) | 1986-03-11 | — | — | US | disclosed |
| US-4560781-A | ANTITOMOR AGENTS-RODENTS | SHIONOGI & CO., LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| EP-0127884-A1 | Novel glycolic acid type platinum complexes | SHIONOGI & CO., LTD. (JP) | 1984-12-12 | — | — | EP | disclosed |
| EP-0112591-A1 | Novel glycolic acid platinum complexes | SHIONOGI & CO., LTD. (JP) | 1984-07-04 | — | — | EP | disclosed |
| EP-0057023-A1 | Novel platinum complexes | SHIONOGI & CO., LTD. (JP) | 1982-08-04 | — | — | EP | disclosed |