Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 5/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687476 | 0.90 | CUL4A (0.36) | DPP4CHRM2DRD1ADRB2TOP2A | |
| SCHEMBL5422476 | 0.86 | ADRB2 (0.51) | DPP4CHRM2DRD1ADRB2TOP2A | |
| SCHEMBL10586160 | 0.85 | DPP4 (0.40) | DPP4CHRM2DRD1ADRB2TOP2A | |
| SCHEMBL4774919 | 0.85 | DPP4 (0.44) | DPP4CHRM2DRD1TOP2ATOP2B | |
| SCHEMBL7823482 | 0.83 | LMNA (0.45) | KDM4ELMNAHSD17B10ABCC4ALDH1A1 | |
| SCHEMBL9416462 | 0.82 | TNF (0.35) | KDM4ELMNAABCC4ALDH1A1MAPT | |
| SCHEMBL10585799 | 0.82 | ADRB2 (0.37) | DPP4CHRM2DRD1ADRB2TOP2A | |
| SCHEMBL10586645 | 0.82 | DPP4 (0.38) | DPP4CHRM2DRD1ADRB2TOP2A | |
| SCHEMBL7819278 | 0.82 | KDM4E (0.45) | ADRB2TOP2ATOP2BKDM4ELMNA | |
| SCHEMBL7824025 | 0.81 | KDM4E (0.48) | ADRB2TOP2ATOP2BKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0963977-B1 | Process for the preparation of quinolone- and naphthyridonecarboxylic acids and their esters | BAYER AG (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-0828715-B1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-0704443-B1 | Quinolone and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 2000-12-27 | — | — | EP | disclosed |
| EP-0963977-A1 | Process for the preparation of quinolone- and naphthyridonecarboxylic acids and their esters | Bayer Aktiengesellschaft (DE) | 1999-12-15 | — | — | EP | disclosed |
| EP-0705828-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1999-12-01 | — | — | EP | disclosed |
| EP-0828715-A1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 1998-03-18 | — | — | EP | disclosed |
| EP-0721948-B1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996038417-A1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-05 | — | — | WO | disclosed |
| EP-0721948-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0704443-A2 | Quinolone and naphthyridone carboxylic acid derivatives | BAYER AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0520277-A2 | 7-Azaisoindolinyl-quinolone- and naphthyridoncarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0520240-A1 | 7-Isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0187376-B1 | 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0310917-A2 | Quinolonecarboxylic acids bearing C(7) carbon-functionality and a method for their preparation | BAYER AG (DE) | 1989-04-12 | — | — | EP | disclosed |
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |