Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241096 | 0.88 | LMNA (0.49) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL3977245 | 0.84 | ALDH1A1 (0.53) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10587033 | 0.84 | GABRA2 (0.41) | ALDH1A1TSHRKDM4EMAPK1HPGD | |
| SCHEMBL7095727 | 0.83 | DPP4 (0.40) | LMNAALDH1A1MAPTABCC4KDM4E | |
| SCHEMBL8130696 | 0.83 | GABRA2 (0.42) | LMNAALDH1A1TSHRPOLBKMT2A | |
| SCHEMBL7103475 | 0.83 | EPHA2 (0.42) | LMNAALDH1A1TSHRMAPTTHRB | |
| SCHEMBL10913668 | 0.81 | LMNA (0.71) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10911159 | 0.80 | POLB (0.50) | LMNAALDH1A1TSHRPOLBKMT2A | |
| SCHEMBL3814272 | 0.80 | TSHR (0.41) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL7817695 | 0.79 | KMT2A (0.54) | LMNAALDH1A1TSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828715-B1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-0310917-A2 | Quinolonecarboxylic acids bearing C(7) carbon-functionality and a method for their preparation | BAYER AG (DE) | 1989-04-12 | — | — | EP | disclosed |
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |