Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792613 | 0.98 | NAAA (0.48) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL6740281 | 0.92 | ALDH1A1 (0.50) | NAAAEPHX1TSHRHCAR2CA1 | |
| SCHEMBL7222931 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7217974 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL1291018 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL6744018 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7224973 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7218977 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL7223934 | 0.90 | NAAA (0.57) | NAAAEPHX1TSHRHCAR2RAD52 | |
| SCHEMBL5551821 | 0.88 | NAAA (0.55) | NAAAEPHX1TSHRHCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| WO-2003089577-A2 | ANTIHELMINTHIC ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |
| US-4942226-A | ANTITUMOR AGENTS, RADIATION SENSITIZERS | MERCK & CO., INC. (US) | 1990-07-17 | — | — | US | disclosed |