SCHEMBL7218977

SCHEMBL7218977

CCCCCCCCCOC(=O)C(CC)CC

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.57
EPHX1 P07099 1/20 0.53
TSHR P16473 3/20 0.52
HCAR2 Q8TDS4 1/20 0.48
RAD52 P43351 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ALDH1A1 P00352 2/20 0.47
FAAH O00519 1/20 0.47
LMNA P02545 1/20 0.47
ACHE P22303 6/20 0.47
DGKA P23743 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7222931 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL1291018 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL7224973 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL7217974 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL7223934 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL6744018 1.00 NAAA (0.57) NAAAEPHX1TSHRHCAR2RAD52
Ammonia Solution, Strong SCHEMBL27907656 0.98 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL6050223 0.98 NAAA (0.54) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL5551821 0.94 NAAA (0.55) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL1759482 0.91 ALDH1A1 (0.56) NAAAEPHX1TSHRHCAR2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011569-B2 Process for synthesizing oxidized lactam compounds ALKERMES PHARMA IRELAND LIMITED (IE) 2018-07-03 US disclosed
US-20170267639-A1 Process for Synthesizing Oxidized Lactam Compounds JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2017-09-21 US disclosed
CN-1190477-C Lubrication oil for refrigerator, hydraulic fluid compoistion for refrigerator and method for lubrication of refrigerator NEW JAPAN CHEMICALS CO LTD (JP) 2005-02-23 CN disclosed
US-6667285-B1 Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability NEW JAPAN CHEMICAL CO., LTD. (JP) 2003-12-23 US disclosed
EP-1225213-A1 LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-24 EP disclosed
CN-1349555-A Lubrication oil for refrigerator, hydraulic fluid compoistion for refrigerator and method for lubrication of refrigerator NEW JAPAN CHEMICALS CO LTD (JP) 2002-05-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267639-A1 Process for Synthesizing Oxidized Lactam Compounds COASY, DHPS, OXA1L NAAA 1441/4885EPHX1 800/4885TSHR 4488/4885
US-10011569-B2 Process for synthesizing oxidized lactam compounds COASY, DHPS, OXA1L NAAA 1441/4885EPHX1 800/4885TSHR 4488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.