Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408460 | 0.86 | MAPT (0.41) | MAPTPKMMAPK1ALDH1A1 | |
| SCHEMBL8128189 | 0.79 | MAPT (0.38) | MAPTPKMMAPK1ALDH1A1 | |
| SCHEMBL6780468 | 0.75 | HPGD (0.43) | MAPTMAPK1ALDH1A1 | |
| SCHEMBL7097723 | 0.75 | BCAT1 (0.47) | MAPTPKMMAPK1ALDH1A1 | |
| SCHEMBL7098719 | 0.75 | RXFP1 (0.37) | ALDH1A1 | |
| SCHEMBL7670892 | 0.75 | AR (0.31) | — | |
| SCHEMBL7038526 | 0.75 | ESPL1 (0.35) | MAPTPKMALDH1A1CYP3A4 | |
| SCHEMBL7015227 | 0.74 | BCAT1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL7026595 | 0.74 | BCAT1 (0.41) | MAPTALDH1A1CYP3A4 | |
| SCHEMBL9189042 | 0.73 | BCAT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032807-A1 | Method for the production of 1-amino -3-aryl -uracils | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
| EP-1257540-A1 | METHOD FOR THE PRODUCTION OF 1-AMINO-3-ARYL-URACILS | Bayer Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001058883-A1 | METHOD FOR THE PRODUCTION OF 1-AMINO-3-ARYL-URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032807-A1 | Method for the production of 1-amino -3-aryl -uracils | NQO2, QARS1, NUDT1 | MAPT 4832/4885PKM 4657/4885MAPK1 3602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.