Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29221790 | 0.81 | ALDH1A1 (0.62) | GAAKMT2ACYP2D6CYP2C19TSHR | |
| SCHEMBL11565084 | 0.80 | OPRM1 (0.55) | GAAKMT2ACYP2D6CYP2C19TSHR | |
| SCHEMBL11568815 | 0.80 | NPC1 (0.50) | KMT2ATSHRMEN1ALDH1A1LMNA | |
| SCHEMBL4793277 | 0.80 | GAA (0.50) | GAAKMT2ACYP2D6CYP2C19TSHR | |
| SCHEMBL3822994 | 0.79 | ALDH1A1 (0.53) | GAAKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL23686835 | 0.79 | NPC1 (0.62) | KMT2AMEN1OPRM1OPRL1HPGD | |
| SCHEMBL5013102 | 0.79 | KMT2A (0.51) | GAAKMT2ACYP2D6CYP2C19TSHR | |
| SCHEMBL28643707 | 0.78 | NPC1 (0.50) | KMT2ATSHRMEN1HPGDALDH1A1 | |
| SCHEMBL6020341 | 0.78 | POLB (0.50) | GAAALDH1A1NPSR1RAB9AMCL1 | |
| SCHEMBL3073770 | 0.77 | CYP2D6 (0.46) | GAAKMT2ACYP2D6CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084523-A1 | USE OF A N,N'-DIBENZYL-THIOUREA AS MEDICINE | WANDJI THOMAS (CM) | 2003-10-16 | — | — | WO | disclosed |