Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936984 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL29221787 | 0.79 | NPC1 (0.63) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7096077 | 0.79 | GAA (0.49) | ALDH1A1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL2428039 | 0.78 | CASR (0.63) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1064750 | 0.78 | ALDH1A1 (0.51) | ALDH1A1PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24576223 | 0.77 | NPC1 (0.71) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL16562180 | 0.77 | ALDH1A1 (0.69) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL1695235 | 0.75 | NPC1 (0.66) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL2721206 | 0.75 | ALDH1A1 (0.65) | ALDH1A1PKMNPC1RAB9AMEN1 | |
| SCHEMBL15514376 | 0.75 | ALDH1A1 (0.65) | ALDH1A1PKMNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479370-B1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | USA (US) | 2009-07-08 | — | — | EP | disclosed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1280495-B1 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | US AGRICULTURE (US) | 2006-11-22 | — | — | EP | disclosed |
| US-7053243-B2 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION (US) | 2006-05-30 | — | — | US | disclosed |
| EP-1479370-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | The United States of America (US) | 2004-11-24 | — | — | EP | disclosed |
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | SECRETARY OF AGRICULTURE | 2004-02-12 | — | — | US | disclosed |
| US-6653505-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-11-25 | — | — | US | disclosed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | disclosed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | disclosed |
| EP-1280495-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | Abbott, Thomas, P. (US) | 2003-02-05 | — | — | EP | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2001-12-27 | — | — | US | disclosed |
| WO-2001085681-A2 | 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME | THE FANNING CORPORATION (US) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040030188-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885PKM 2458/4885NPC1 544/4885 |
| US-20010056205-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885PKM 2458/4885NPC1 544/4885 |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885PKM 2458/4885NPC1 544/4885 |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | ALDH1A1 754/4885PKM 2458/4885NPC1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.