Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994163 | 0.85 | EPHX2 (0.61) | LMNAMAPTCYP3A4KMT2ACYP1A2 | |
| SCHEMBL20379023 | 0.84 | LMNA (0.62) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL2532397 | 0.83 | LMNA (0.78) | LMNAMAPTENPP2MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL28701756 | 0.81 | LMNA (0.75) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL270275 | 0.81 | MAPT (0.58) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL18290496 | 0.81 | CYP3A4 (0.47) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL1882019 | 0.81 | CYP3A4 (0.47) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL4883098 | 0.80 | CD38 (0.53) | LMNAMAPTCYP3A4KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL17583800 | 0.79 | CYP3A4 (0.46) | LMNAMAPTENPP2MKNK1MKNK2 | |
| SCHEMBL3250899 | 0.79 | CYP3A4 (0.71) | LMNAMAPTENPP2MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229455-A1 | Bicyclic [3.1.0.] heteroaryl amides as type 1 glycine transport inhibitors | PFIZER INC. | 2006-10-12 | — | — | US | claimed |
| EP-4712965-A2 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | Springworks Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| CN-119627204-A | Solid electrolyte and precursor thereof | 香港科技大学 | 2025-03-14 | — | — | CN | disclosed |
| US-20240383891-A1 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2024-11-21 | — | — | US | disclosed |
| WO-2024238738-A2 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-2467398-B1 | TRPC4 INHIBITORS AND USES THEREOF | POSEIDA THERAPEUTICS INC (US) | 2019-10-09 | — | — | EP | disclosed |
| CN-108349904-A | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | 米托布里奇公司 | 2018-07-31 | — | — | CN | disclosed |
| US-9018394-B2 | Method for producing aromatic compound having ring structure that includes nitrogen atom or oxygen atom | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20130338371-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING RING STRUCTURE THAT INCLUDES NITROGEN ATOM OR OXYGEN ATOM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2013-12-19 | — | — | US | disclosed |
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRANSPOSAGEN BIOPHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| EP-1509502-A1 | METHOD OF FORMING A CARBON-CARBON OR CARBON-HETEROATOM LINKAGE | RHODIA CHIMIE (FR) | 2005-03-02 | — | — | EP | disclosed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |
| WO-2003101966-A1 | METHOD OF FORMING A CARBON-CARBON OR CARBON-HETEROATOM LINKAGE | RHODIA CHIMIE (FR) | 2003-12-11 | — | — | WO | disclosed |
| EP-1337516-A1 | PROCESS FOR MANUFACTURE OF IMIDAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002040454-A1 | PROCESS FOR MANUFACTURE OF IMIDAZOLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2002-05-23 | — | — | WO | disclosed |
| US-6177575-B1 | CONTACTING IN THE LIQUID PHASE AMMONIUM CARBONATE OR AMMONIUM BICARBONATE, A GLYOXAL, AN ALDEHYDE, AND OPTIONALLY AN AMINE | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-01-23 | — | — | US | disclosed |
| CN-1218801-A | Tri-substituted imidazoles, and process of their preparation and using the same and having their pharmic composition | SMITHKLINE BEECHAM CORP (US) | 1999-06-09 | — | — | CN | disclosed |
| CN-1129447-A | Trisubstituted imidazoles having multiple therapeutic effects | SMITHKLINE BEECHAM CORP (US) | 1996-08-21 | — | — | CN | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383891-A1 | BENZIMIDAZOLE AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD2, TEAD1 | LMNA 1774/4885MAPT 2668/4885ENPP2 2881/4885 |
| US-20130338371-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND HAVING RING STRUCTURE THAT INCLUDES NITROGEN ATOM OR OXYGEN ATOM | TH, AOC3, NOX3 | LMNA 2611/4885MAPT 3111/4885ENPP2 4032/4885 |
| US-20120148604-A1 | TRP INHIBITORS AND USES THEREOF | TRPC4, TRPC1, TRPC3 | LMNA 4221/4885MAPT 2884/4885ENPP2 733/4885 |
| US-20060229455-A1 | Bicyclic [3.1.0.] heteroaryl amides as type 1 glycine transport inhibitors | SLC1A2, SLC1A1, GLRA1 | LMNA 4301/4885MAPT 1815/4885ENPP2 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.