Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650154 | 0.81 | KMT2A (0.68) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11782142 | 0.79 | KMT2A (0.83) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL1098345 | 0.79 | RAB9A (0.77) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL14890950 | 0.78 | RAB9A (0.74) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11572863 | 0.76 | RAB9A (0.71) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL10628022 | 0.76 | CYP2C19 (0.58) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL10705364 | 0.76 | MAPT (0.70) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL6537209 | 0.76 | RAB9A (0.71) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL28034394 | 0.75 | KMT2A (0.61) | RAB9AKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL7634773 | 0.74 | SMN1; SMN2 (0.68) | RAB9AKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349860-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002068422-A2 | SYNTHESES FOR PREPARING 1,4-DIKETOPYRROLO[3,4-C]PYRROLES | SUN CHEMICAL CORPORATION (US) | 2002-09-06 | — | — | WO | disclosed |