⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065687 | 0.76 | — | — | |
| SCHEMBL3055446 | 0.69 | AKT1 (0.52) | — | |
| SCHEMBL14911633 | 0.66 | NOS1 (0.58) | — | |
| SCHEMBL20818730 | 0.65 | ADRB2 (0.42) | — | |
| SCHEMBL20817850 | 0.65 | TRPC5 (0.58) | — | |
| SCHEMBL20831227 | 0.64 | POLB (0.68) | — | |
| SCHEMBL1246645 | 0.63 | — | — | |
| SCHEMBL1475950 | 0.63 | — | — | |
| SCHEMBL2419069 | 0.62 | NOS1 (0.55) | — | |
| SCHEMBL4564464 | 0.62 | HSD17B10 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010910-A | Biazacycloalkane Menin-MLL protein inhibitor, pharmaceutical composition and application thereof | 赛诺哈勃药业（成都）有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12617782-B2 | Pyridazinones as PARP7 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| WO-2025245484-A1 | FOXN1 ACTIVATORS | THYMOFOX INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-12435078-B2 | Pyridazinones and methods of use thereof | GFB (ABC), LLC (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250270223-A1 | CRYSTAL OF SUBSTITUTED PIPERAZINE DERIVATIVE AND PREPARATION METHOD THEREFOR | Kangbaida (Sichuan) Biotechnology Co., Ltd (CN) | 2025-08-28 | — | — | US | disclosed |
| US-12371421-B2 | Solid forms of a PARP7 inhibitor | RIBON THERAPEUTICS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20250236621-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN INC. | 2025-07-24 | — | — | US | disclosed |
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| CN-116444497-B | Pyridazinone compound, preparation and application thereof | 如东凌达生物医药科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2025076236-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-1992012137-A1 | NOVEL 3(2H)-PYRIDAZINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1992-07-23 | — | — | WO | disclosed |
| EP-0201765-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4978665-A | ANTIALLERGENS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| US-4892947-A | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0275997-A1 | 3(2H)pyridazinone, process for its preparation and antagonistic agent against SRS-A containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |
| EP-0201765-A2 | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-11-20 | — | — | EP | disclosed |
| US-4532239-A | N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0054946-B1 | BASIC SUBSTITUTED PYRIDAZINES, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0054946-A1 | Basic substituted pyridazines, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1982-06-30 | — | — | EP | disclosed |
| US-4008086-A | PYRIDONE OR PYRIDAZONE DERIVATIVES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |