Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18643783 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL7096502 | 0.80 | TSHR (0.37) | — | |
| SCHEMBL7101062 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL7095855 | 0.77 | TSHR (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7099974 | 0.75 | HCAR2 (0.33) | CA1CA2ALDH1A1 | |
| SCHEMBL275280 | 0.74 | SMN1; SMN2 (0.52) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL10805452 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL26658220 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL31111331 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL23009543 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |