Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101062 | 0.82 | ALDH1A1 (0.38) | ALDH1A1GAA | |
| SCHEMBL7099974 | 0.78 | HCAR2 (0.33) | TSHRALDH1A1 | |
| SCHEMBL2275427 | 0.78 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7096487 | 0.77 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7097266 | 0.76 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7096502 | 0.75 | TSHR (0.37) | TSHR | |
| SCHEMBL22883305 | 0.72 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL9478200 | 0.72 | TSHR (0.52) | TSHRALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7096884 | 0.71 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL7101799 | 0.71 | TSHR (0.38) | TSHRALDH1A1SMN1; SMN2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |