Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593173 | 0.80 | ALDH1A1 (0.72) | ALDH1A1POLBAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL6715659 | 0.73 | ENPP1 (0.42) | ALDH1A1AURKAKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL868954 | 0.72 | KDM4E (0.49) | ALDH1A1POLBAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL23925371 | 0.71 | KDM4E (0.48) | ALDH1A1POLBAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL11476738 | 0.70 | ALDH1A1 (0.74) | ALDH1A1KDM4ESMN1; SMN2MAPK1MAPT | |
| SCHEMBL14506996 | 0.70 | KDM4E (0.52) | ALDH1A1POLBKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL7196374 | 0.69 | ALDH1A1 (0.40) | ALDH1A1POLBAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL9770306 | 0.69 | ALDH1A1 (0.42) | ALDH1A1POLBAURKAKDM4ESMN1; SMN2 | |
| SCHEMBL8943817 | 0.69 | KDM4E (0.69) | ALDH1A1POLBKDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL15452766 | 0.67 | KDM4E (0.74) | ALDH1A1POLBKDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345940-A2 | TRIAZOLOPYRIMIDINES | Bayer CropScience K.K. (JP) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051845-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE K.K. (DE) | 2002-07-04 | — | — | WO | disclosed |