SCHEMBL709673

SCHEMBL709673

C#Cc1ccc(C#Cc2ccc(OC)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.63
KCNH2 Q12809 1/20 0.53
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA12 O43570 1/20 0.50
CA14 Q9ULX7 1/20 0.50
ACACB O00763 3/20 0.45
MCHR1 Q99705 1/20 0.45
ACHE P22303 1/20 0.42
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GRM3 Q14832 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
HAO1 Q9UJM8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187127 0.93 CA1 (0.58) APPKCNH2CA1CA2CA7
SCHEMBL31403396 0.91 CA1 (0.55) APPKCNH2CA1CA2CA7
SCHEMBL30998823 0.91 CA1 (0.55) APPKCNH2CA1CA2CA7
SCHEMBL30998827 0.91 CA1 (0.55) APPKCNH2CA1CA2CA7
SCHEMBL30998834 0.91 CA1 (0.55) APPKCNH2CA1CA2CA7
SCHEMBL10033202 0.89 APP (0.52) APPKCNH2CA1CA2CA7
SCHEMBL10300057 0.88 APP (0.77) APPKCNH2CA1CA2CA7
SCHEMBL674764 0.88 APP (0.77) APPKCNH2CA1CA2CA7
SCHEMBL4552830 0.86 LTA4H (0.54) APPKCNH2CA1CA2CA7
SCHEMBL9715639 0.85 APP (0.74) APPKCNH2CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102881296-B Optical data carrier records method and the optical data carrier of data 通用电气公司 2016-07-06 CN claimed
CN-102881296-B Optical data carrier records method and the optical data carrier of data 通用电气公司 2016-07-06 CN disclosed
US-8703388-B2 Optical data storage media GENERAL ELECTRIC COMPANY (US) 2014-04-22 US disclosed
EP-2290408-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-08-15 EP disclosed
US-20120163145-A1 OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2012-06-28 US disclosed
US-8124299-B2 Methods for using optical data storage media GENERAL ELECTRIC COMPANY (US) 2012-02-28 US disclosed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 US disclosed
EP-2290408-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 EP disclosed