Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083164 | 0.94 | IDO1 (0.40) | IDO1GAAMEN1KMT2ATDP1 | |
| SCHEMBL7083158 | 0.88 | IDO1 (0.43) | IDO1GAAMEN1KMT2ATDP1 | |
| SCHEMBL7078640 | 0.80 | MTNR1A (0.59) | IDO1GAAKMT2AALDH1A1HPGD | |
| SCHEMBL7528860 | 0.79 | MTNR1A (0.62) | IDO1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL1742579 | 0.79 | CA12 (0.54) | GAAMEN1KMT2ATDP1STK17B | |
| SCHEMBL3716262 | 0.78 | IDO1 (0.47) | IDO1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10493769 | 0.77 | IDO1 (0.46) | IDO1GAATDP1ALDH1A1MAPT | |
| SCHEMBL31490568 | 0.76 | IDO1 (0.48) | IDO1GAAMEN1KMT2ATDP1 | |
| SCHEMBL25925015 | 0.75 | KMT2A (0.47) | GAAMEN1KMT2ATDP1KDM4E | |
| SCHEMBL7894530 | 0.75 | MTNR1A (0.48) | IDO1TDP1ALDH1A1HPGDNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003081209-A2 | IDENTIFICATION OF LIGANDS FOR A RECEPTOR FAMILY AND RELATED METHODS | TRIAD THERAPEUTICS, INC. (US) | 2003-10-02 | — | — | WO | disclosed |