Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SDCBP | O00560 | 1/20 | 0.44 |
| ▸ | SDC2 | P34741 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015112 | 0.87 | ALDH1A1 (0.53) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL24671054 | 0.87 | IDO1 (0.49) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL18295921 | 0.87 | L3MBTL1 (0.55) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL7528860 | 0.87 | MTNR1A (0.62) | MTNR1AMTNR1BIDO1ALDH1A1MALT1 | |
| SCHEMBL21013091 | 0.86 | SDCBP (0.47) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL3716262 | 0.86 | IDO1 (0.47) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL20837980 | 0.85 | KMT2A (0.47) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL445683 | 0.85 | ALDH1A1 (0.48) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL10493769 | 0.84 | IDO1 (0.46) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 | |
| SCHEMBL4612706 | 0.84 | IDO1 (0.46) | MTNR1AMTNR1BIDO1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |
| US-6171520-B1 | Reagents for labeling SH groups, process for the preparation of them and method for labeling with them | SS PHARMACEUTICAL CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0844246-A1 | REAGENTS FOR LABELING SH GROUPS, PROCESS FOR THE PREPARATION OF THEM, AND METHOD FOR LABELING WITH THEM | SS Pharmaceutical Co., Ltd. (JP) | 1998-05-27 | — | — | EP | disclosed |