SCHEMBL7096783

SCHEMBL7096783

CC(=O)COC(=O)[C@@H]1CCCN1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.40
DPP4 P27487 4/20 0.37
DPP7 Q9UHL4 2/20 0.37
DPP8 Q6V1X1 2/20 0.37
DPP9 Q86TI2 2/20 0.37
FAP Q12884 1/20 0.37
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SCN4A P35499 1/20 0.35
ELANE P08246 1/20 0.34
TLR2 O60603 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14761896 0.84 NOS2 (0.38) PRCPDPP4DPP7DPP8DPP9
SCHEMBL10519805 0.83 PRCP (0.41) PRCPDPP4DPP7DPP8DPP9
SCHEMBL6876323 0.82 NOS2 (0.46) PRCPDPP4DPP7DPP8DPP9
SCHEMBL133135 0.81 PRCP (0.45) PRCPDPP4DPP7DPP8DPP9
SCHEMBL10829027 0.81 PRCP (0.45) PRCPDPP4DPP7DPP8DPP9
SCHEMBL3330660 0.81 PRCP (0.45) PRCPDPP4DPP7DPP8DPP9
SCHEMBL115996 0.81 PRCP (0.45) PRCPDPP4DPP7DPP8DPP9
Hydrochloric Acid SCHEMBL10519803 0.81 PRCP (0.40) PRCPDPP4DPP7DPP8DPP9
SCHEMBL8815499 0.81 DPP4 (0.38) PRCPDPP4DPP7DPP8DPP9
SCHEMBL2010421 0.81 NOS2 (0.42) PRCPDPP4DPP7DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0895990-B1 Method for the preparation of 1-pyruvyl-L-proline DSM FINE CHEM AUSTRIA GMBH (AT) 2003-09-03 EP claimed