Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096783 | 0.81 | PRCP (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL14761896 | 0.80 | NOS2 (0.38) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9680371 | 0.79 | DPP4 (0.37) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10519805 | 0.79 | PRCP (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6876323 | 0.78 | NOS2 (0.46) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL3330660 | 0.78 | PRCP (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10829027 | 0.78 | PRCP (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL133135 | 0.78 | PRCP (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL115996 | 0.78 | PRCP (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL18823540 | 0.77 | DPP4 (0.38) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |