Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.58 |
| ▸ | FEN1 | P39748 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087897 | 0.92 | KMT2A (0.51) | ERCC5FEN1PTPN1KMT2AMEN1 | |
| SCHEMBL6365441 | 0.90 | HAO1 (0.63) | ERCC5FEN1PTPN1KMT2AMEN1 | |
| SCHEMBL19545100 | 0.88 | ERCC5 (0.68) | ERCC5FEN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2911004 | 0.86 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL9208969 | 0.84 | ALDH1A1 (0.57) | ERCC5FEN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12020298 | 0.84 | ESR1 (0.58) | PTPN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL12182346 | 0.84 | SMN1; SMN2 (0.51) | ERCC5FEN1PTPN1KMT2AMEN1 | |
| SCHEMBL2910361 | 0.83 | SMN1; SMN2 (0.57) | ERCC5FEN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1109662 | 0.83 | ERCC5 (0.64) | ERCC5FEN1PTPN1KMT2AMEN1 | |
| SCHEMBL25011313 | 0.83 | ALDH1A1 (0.56) | ERCC5FEN1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087561-A1 | RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS | SIKA TECHNOLOGY AG (CH) | 2026-04-30 | — | — | WO | claimed |
| EP-4733284-A1 | RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS | Sika Technology AG (CH) | 2026-04-29 | — | — | EP | claimed |
| EP-4063422-A1 | 1,3-DICARBONYL COMPOUNDS AS RETARDING ADDITIVES FOR UCRETE SYSTEMS | Construction Research & Technology GmbH (DE) | 2022-09-28 | — | — | EP | claimed |
| CN-103898072-B | A kind of Ketoreductase mutant and application thereof | HANGZHOU NORMAL UNIVERSITY (CN) | 2016-03-16 | — | — | CN | claimed |
| CN-103898072-A | Ketoreductase mutant and application thereof | UNIV HANGZHOU NORMAL | 2014-07-02 | — | — | CN | claimed |
| WO-2026087561-A1 | RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS | SIKA TECHNOLOGY AG (CH) | 2026-04-30 | — | — | WO | disclosed |
| EP-4733284-A1 | RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS | Sika Technology AG (CH) | 2026-04-29 | — | — | EP | disclosed |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | KINETA INC (US) | 2025-11-20 | — | — | US | disclosed |
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-4444312-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. | 2024-06-27 | — | — | US | disclosed |
| US-4211709-A | ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-08 | — | — | US | disclosed |
| US-4198502-A | ANTIINFLAMMATORY AGENT, CNS DEPRESSANTS, ANALGESICS, ANTIPYRETICS, ANTIULCER AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-04-15 | — | — | US | disclosed |
| US-4190726-A | Polycyclic dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4140696-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS AND CNS DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1979-02-20 | — | — | US | disclosed |
| EP-0000541-A2 | 1H-Pyrimido-(4,5-c)-1,2-diazepines, methods for their preparation and compositions containing them; their use as intermediates for heterocyclic transformations. | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-02-07 | — | — | EP | disclosed |
| EP-0000383-A1 | Pyrimido (4,5-c) pyridazines, their use in pharmaceutical preparations, and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-01-24 | — | — | EP | disclosed |
| EP-0000382-A1 | Pyrimido (4,5-c)pyridazines, compositions containing them and processes for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-01-24 | — | — | EP | disclosed |
| US-4007180-A | POLYESTERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208923-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | SLC18A2, SLC6A19, SLC1A1 | ERCC5 3785/4885FEN1 3013/4885PTPN1 3751/4885 |
| US-20260085073-A1 | PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY | MALT1, BCL6, BCL3 | ERCC5 4283/4885FEN1 1981/4885PTPN1 353/4885 |
| US-20250353851-A1 | PURINES AND METHODS OF THEIR USE | TDP1, TDP2, PIKFYVE | ERCC5 654/4885FEN1 82/4885PTPN1 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.