Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096811 | 0.93 | HCAR2 (0.43) | TSHRTHRBALDH1A1HCAR2POLB | |
| SCHEMBL865331 | 0.86 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL865332 | 0.82 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17240329 | 0.82 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7096813 | 0.79 | HCAR2 (0.47) | TSHRTHRBALDH1A1HCAR2ATM | |
| SCHEMBL10714365 | 0.78 | TSHR (0.44) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1428431 | 0.77 | ALDH1A1 (0.48) | TSHRTHRBALDH1A1HCAR2ATM | |
| SCHEMBL8610770 | 0.77 | ALDH1A1 (0.48) | TSHRTHRBALDH1A1HCAR2ATM | |
| SCHEMBL17240327 | 0.76 | TSHR (0.45) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4647263 | 0.76 | TSHR (0.41) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272581-A2 | CURABLE POLYMERIC COMPOSITIONS | SARTOMER COMPANY, INC. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001057094-A2 | CURABLE POLYMERIC COMPOSITIONS | SARTOMER COMPANY, INC. (US) | 2001-08-09 | — | — | WO | disclosed |