Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 12/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096811 | 0.87 | HCAR2 (0.43) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL4017018 | 0.80 | HCAR2 (0.48) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| Maleic Acid SCHEMBL5086355 | 0.80 | HCAR2 (0.48) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL7949238 | 0.80 | HCAR2 (0.48) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL28369736 | 0.80 | HCAR2 (0.54) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL7096809 | 0.79 | TSHR (0.42) | HCAR2TSHRALDH1A1TDP1THRB | |
| SCHEMBL10688851 | 0.78 | HCAR2 (0.57) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL868206 | 0.78 | HCAR2 (0.57) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL868207 | 0.78 | HCAR2 (0.57) | HCAR2TSHRALDH1A1KDM4EMAPT | |
| Maleic Acid SCHEMBL8429487 | 0.78 | ALDH1A1 (0.46) | HCAR2TSHRALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272581-A2 | CURABLE POLYMERIC COMPOSITIONS | SARTOMER COMPANY, INC. (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001057094-A2 | CURABLE POLYMERIC COMPOSITIONS | SARTOMER COMPANY, INC. (US) | 2001-08-09 | — | — | WO | disclosed |