Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096051 | 0.88 | PPARG (0.43) | APAF1PPARGHDAC6 | |
| SCHEMBL6426492 | 0.88 | APAF1 (0.40) | APAF1 | |
| SCHEMBL7102086 | 0.86 | APAF1 (0.47) | APAF1HDAC6 | |
| SCHEMBL7103133 | 0.85 | AGTR1 (0.39) | APAF1PPARGHDAC6GAA | |
| SCHEMBL7100218 | 0.85 | KDM4E (0.39) | APAF1PPARGHDAC6 | |
| SCHEMBL7098112 | 0.85 | AGTR1 (0.41) | APAF1GAA | |
| SCHEMBL7099617 | 0.83 | TP53 (0.43) | PPARG | |
| SCHEMBL7097958 | 0.82 | PPARG (0.38) | PPARG | |
| SCHEMBL7097769 | 0.81 | KMT2A (0.44) | — | |
| SCHEMBL7102589 | 0.81 | APAF1 (0.36) | APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |