Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098112 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2MEN1KMT2AGAA | |
| SCHEMBL7100111 | 0.87 | BACE1 (0.43) | MEN1KMT2ATBXA2RPPARGAPAF1 | |
| SCHEMBL7100218 | 0.87 | KDM4E (0.39) | MEN1KMT2AHDAC6PPARGAPAF1 | |
| SCHEMBL7102086 | 0.87 | APAF1 (0.47) | MEN1KMT2AHDAC6TP53APAF1 | |
| SCHEMBL7096854 | 0.85 | APAF1 (0.39) | GAAHDAC6PPARGAPAF1 | |
| SCHEMBL7096051 | 0.84 | PPARG (0.43) | AGTR1AGTR2HDAC6PPARGAPAF1 | |
| SCHEMBL7097769 | 0.84 | KMT2A (0.44) | MEN1KMT2ARAB9A | |
| SCHEMBL6426492 | 0.82 | APAF1 (0.40) | MEN1KMT2AAPAF1 | |
| SCHEMBL7097958 | 0.80 | PPARG (0.38) | MEN1KMT2APPARG | |
| SCHEMBL7099617 | 0.79 | TP53 (0.43) | MEN1KMT2APPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |