Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365070 | 0.83 | HTR1A (0.52) | HTR1AMAPTRIPK1KDM4ECCNT1 | |
| SCHEMBL3857798 | 0.79 | SMN1; SMN2 (0.47) | HTR1AMAPTRIPK1HTR3EHTR3B | |
| SCHEMBL2144142 | 0.79 | KMT2A (0.65) | HTR1AMAPTALDH1A1KMT2AHTT | |
| SCHEMBL14127817 | 0.78 | KDM4E (0.55) | MAPTRIPK1KDM4ECCNT1CDK9 | |
| SCHEMBL14125084 | 0.77 | KDM4E (0.45) | MAPTRIPK1KDM4ECCNT1CDK9 | |
| SCHEMBL5873519 | 0.77 | PGK1 (0.47) | MAPTRIPK1KDM4ECCNT1CDK9 | |
| SCHEMBL3267478 | 0.77 | MAPT (0.60) | HTR1AMAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7102720 | 0.76 | ALDH1A1 (0.60) | HTR1AMAPTKDM4EALDH1A1TTR | |
| SCHEMBL9881001 | 0.74 | MAPT (0.39) | MAPTKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL646725 | 0.74 | TTR (0.53) | MAPTKDM4EHTR3EHTR3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082286-A1 | QUINOLINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHEMON INC. (KR) | 2003-10-09 | — | — | WO | disclosed |