Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1873263 | 0.95 | TNK2 (0.51) | TNK2SOS1BTKNAMPTCCNT1 | |
| SCHEMBL1868160 | 0.90 | NAMPT (0.48) | TNK2SOS1NAMPTCCNT1CDK9 | |
| Trifluoroacetic Acid SCHEMBL1878173 | 0.77 | NAMPT (0.42) | TNK2NAMPTCCNT1CDK9 | |
| SCHEMBL30074970 | 0.75 | CNR1 (0.55) | TNK2SOS1NAMPTCCNT1CDK9 | |
| SCHEMBL31336142 | 0.75 | GRM5 (0.51) | NAMPTCCNT1CDK9CNR1CYP11B2 | |
| SCHEMBL8512618 | 0.75 | GRM5 (0.51) | NAMPTCCNT1CDK9CNR1CYP11B2 | |
| SCHEMBL25457026 | 0.74 | CNR1 (0.49) | TNK2CCNT1CDK9CNR1GRM1 | |
| SCHEMBL30993158 | 0.74 | CNR1 (0.51) | TNK2SOS1NAMPTCCNT1CDK9 | |
| Trifluoroacetic Acid SCHEMBL1872651 | 0.74 | RAD52 (0.37) | TNK2NAMPTCCNT1CDK9JAK1 | |
| SCHEMBL25238113 | 0.73 | NAMPT (0.53) | TNK2BTKNAMPTCNR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278732-A1 | 1-AROYL-PIPERIDINYL BENZAMIDINES | Aventis Pharmaceuticals Inc. (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001081310-A1 | 1-AROYL-PIPERIDINYL BENZAMIDINES | AVENTIS PHARMACEUTICALS INC. (US) | 2001-11-01 | — | — | WO | disclosed |