SCHEMBL70977

SCHEMBL70977

O=C(O)c1cccc2oc3cccc(C(=O)O)c3c(=O)c12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.48
ALDH1A1 P00352 5/20 0.46
ALOX15 P16050 1/20 0.46
CYP1A2 P05177 1/20 0.46
MAOB P27338 2/20 0.46
TSHR P16473 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
GPR35 Q9HC97 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
TBK1 Q9UHD2 1/20 0.45
TYMS P04818 1/20 0.44
TTR P02766 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1987428 0.87 MAOA (0.62) HSD17B10ALDH1A1MAOBTBK1TTR
SCHEMBL27697686 0.84 MAOA (0.58) HSD17B10ALDH1A1MAOBTBK1TTR
SCHEMBL29415448 0.81 TTR (0.72) HSD17B10ALDH1A1TBK1TTRMAOA
SCHEMBL2808430 0.81 TTR (0.72) HSD17B10ALDH1A1TBK1TTRMAOA
SCHEMBL516363 0.80 ALDH1A1 (0.54) HSD17B10ALDH1A1ALOX15MAOBTSHR
SCHEMBL29685650 0.80 ALDH1A1 (0.54) HSD17B10ALDH1A1ALOX15MAOBTSHR
SCHEMBL7756950 0.80 MAPK8 (0.43) CA12CA1CA3CA4CA6
SCHEMBL7550966 0.79 KDM4E (0.55) HSD17B10ALDH1A1MAOBTSHRCA12
SCHEMBL7258597 0.78 KMT2A (0.53) HSD17B10ALDH1A1ALOX15CYP1A2MAOB
SCHEMBL7649371 0.76 MAOA (0.41) HSD17B10ALDH1A1ALOX15CYP1A2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 HSD17B10 2777/4885ALDH1A1 1882/4885ALOX15 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.