Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653199 | 0.77 | MAPT (0.33) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL4561581 | 0.74 | — | — | |
| SCHEMBL19953391 | 0.72 | MAPT (0.36) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL7168637 | 0.69 | MAPT (0.38) | MAPTKDM4EALOX15SMN1; SMN2 | |
| SCHEMBL21618434 | 0.69 | MAPT (0.33) | MAPTKDM4ESMN1; SMN2 | |
| Trolamine SCHEMBL15845959 | 0.67 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL1146 | 0.67 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL4748243 | 0.67 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL434089 | 0.67 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2 | |
| Trolamine SCHEMBL16598241 | 0.67 | ALDH1A1 (0.50) | MAPTKDM4EALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618587-A | USING TRISHYDROXYMETHYLAMINOMETHANE AND 2,2 BIS-HYDROXYMETHYL-2,2',2\"-NITRIOLOTRIETHANOL | FISHER SCIENTIFIC COMPANY A CORP OF DE | 1986-10-21 | — | — | US | claimed |
| EP-3807417-A2 | SIALIC ACID TRANSPORTER PROTEINS AS BIOMARKERS AND DRUG TARGETS | Quadram Institute Bioscience (GB) | 2021-04-21 | — | — | EP | disclosed |
| EP-1339434-A2 | CONTACT LENS PACKAGING SOLUTIONS | Johnson & Johnson Vision Care, Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002045759-A2 | CONTACT LENS PACKAGING SOLUTIONS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2002-06-13 | — | — | WO | disclosed |
| EP-0238951-B1 | PARTICLES SUITABLE FOR TABLETTING INTO DIAGNOSTIC REAGENTS | MERCK PATENT GmbH (DE) | 1992-05-13 | — | — | EP | disclosed |
| US-5009994-A | Uniform distribution | EM DIAGNOSTIC SYSTEMS, INC. (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0315187-A1 | Separation of hemoglobin A2 from hemoglobin mixture | BIO-RAD LABORATORIES, INC. (US) | 1989-05-10 | — | — | EP | disclosed |
| EP-0238951-A2 | Particles suitable for tabletting into diagnostic reagents | MERCK PATENT GmbH (DE) | 1987-09-30 | — | — | EP | disclosed |