Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 14/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736526 | 0.84 | KDM4E (0.44) | KDM4EGAAHPGDHSD17B10NOTUM | |
| SCHEMBL15228293 | 0.81 | NOTUM (0.40) | GAAHPGDHSD17B10NOTUMALDH1A1 | |
| SCHEMBL27926911 | 0.81 | KDM4E (0.42) | KDM4EGAAHPGDHSD17B10NOTUM | |
| SCHEMBL4142063 | 0.79 | GABRA1 (0.43) | KDM4EGAAHPGDALDH1A1 | |
| SCHEMBL15329909 | 0.77 | ALDH1A1 (0.45) | KDM4EGAAHPGDHSD17B10NOTUM | |
| SCHEMBL1041466 | 0.77 | NOTUM (0.53) | NOTUMALDH1A1 | |
| SCHEMBL1220842 | 0.77 | ALDH1A1 (0.52) | KDM4EGAAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL22890556 | 0.77 | L3MBTL1 (0.50) | KDM4EGAAHSD17B10NOTUMALDH1A1 | |
| SCHEMBL23900591 | 0.74 | NOTUM (0.42) | KDM4EGAAHPGDHSD17B10NOTUM | |
| SCHEMBL19197220 | 0.73 | BRD4 (0.42) | KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301493-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004444-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |