Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101511 | 0.88 | GABRA2 (0.43) | GABRA2GABRB2GABRB3 | |
| SCHEMBL6976748 | 0.86 | GABRA2 (0.43) | GABRA2GABRB2GABRB3 | |
| SCHEMBL7095243 | 0.86 | GABRA2 (0.43) | GABRA2GABRB2GABRB3 | |
| SCHEMBL7094294 | 0.85 | GABRA2 (0.42) | GABRA2GABRB2GABRB3 | |
| SCHEMBL6969574 | 0.85 | GABRA2 (0.43) | GABRA2GABRB2 | |
| SCHEMBL6972362 | 0.83 | GABRA2 (0.40) | GABRA2GABRB2GABRB3 | |
| SCHEMBL7082653 | 0.83 | GABRA2 (0.40) | GABRA2GABRB2GABRB3 | |
| SCHEMBL6977444 | 0.82 | GABRA2 (0.46) | GABRA2GABRB2GABRB3 | |
| SCHEMBL6055638 | 0.82 | GABRB3 (0.41) | GABRA2GABRB2GABRB3 | |
| SCHEMBL7098237 | 0.82 | GABRA2 (0.40) | GABRA2GABRB2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933363-B1 | Parasiticidal pyrazoles | PFIZER LTD (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-20020173662-A1 | Parasiticidal pyrazoles | BANKS BERNARD JOSEPH (GB) | 2002-11-21 | — | — | US | disclosed |
| US-6090394-A | FOR HUMANS, ANIMALS | PFIZER INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-6019986-A | Parasiticidal pyrazoles | PFIZER INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0933363-A1 | Parasiticidal pyrazoles | Pfizer Limited (GB) | 1999-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173662-A1 | Parasiticidal pyrazoles | HRH3, HRH2, HRH1 | GABRA2 535/4885GABRB2 708/4885GABRB3 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.