SCHEMBL7097913

SCHEMBL7097913

CCCCC(CC)COc1ccc(-c2nc(-c3ccc(OCC(CC)CCCC)cc3)nc(-c3ccc(OCC(CC)CCCC)cc3O)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
ALDH1A1 P00352 6/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
NPC1 O15118 5/20 0.36
RAB9A P51151 4/20 0.36
MAPT P10636 3/20 0.36
CYP3A4 P08684 2/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CA2 P00918 1/20 0.36
KDM4E B2RXH2 3/20 0.36
HSD17B10 Q99714 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
TDP1 Q9NUW8 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
CYP2C19 P33261 2/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17831410 1.00 LMNA (0.39) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL23784451 0.98 LMNA (0.37) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL15805569 0.97 ALDH1A1 (0.38) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL5752606 0.95 ALDH1A1 (0.38) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL17831381 0.95 LMNA (0.35) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL14415462 0.95 LMNA (0.35) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL20024335 0.95 NR5A1 (0.44) ALDH1A1TSHRNPC1RAB9AMAPT
SCHEMBL7895563 0.94 LMNA (0.37) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL10195000 0.94 TDP1 (0.43) LMNAALDH1A1TSHRMAPK1NPC1
SCHEMBL19224811 0.94 NR5A1 (0.37) LMNAALDH1A1TSHRMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170189277-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2017-07-06 US disclosed
US-20150190320-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES L'OREAL (FR) 2015-07-09 US disclosed
US-20150157539-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES L'OREAL (FR) 2015-06-11 US disclosed
US-8882902-B2 Composite pigment and method for preparation thereof L'OREAL (FR) 2014-11-11 US disclosed
US-20130309285-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2013-11-21 US disclosed
US-20130259912-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2013-10-03 US disclosed
US-20100178484-A1 TRANSPARENT POLYMER ARTICLES OF LOW THICKNESS LEPPARD DAVID GEORGE 2010-07-15 US disclosed
US-20090291289-A1 TRANSPARENT POLYMER ARTICLES OF LOW THICKNESS LEPPARD DAVID GEORGE 2009-11-26 US disclosed
US-20090042006-A1 Transparent polymer articles of low thickness LEPPARD DAVID GEORGE 2009-02-12 US disclosed
US-20070259165-A1 Transparent polymer articles of low thickness LEPPARD DAVID G 2007-11-08 US disclosed
US-7166653-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-23 US disclosed
US-7166653-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-23 US disclosed
EP-0743309-B1 o-Hydroxyphenyl-s-triazines as UV stabilisers CIBA SC HOLDING AG (CH) 2003-09-10 EP disclosed
EP-0654469-B1 Stabilised polymers containing o-hydroxyphenyl-s-triazines CIBA SC HOLDING AG (CH) 2001-08-22 EP disclosed
US-5688995-A SUNSCREEN AGENTS CIBA-GEIGY CORPORATION (US) 1997-11-18 US disclosed
US-5591850-A STABILIZERS FOR TEXTILE FIBERS, COSMETIC SUNSCREENS CIBA-GEIGY CORPORATION (US) 1997-01-07 US disclosed
EP-0743309-A1 o-Hydroxyphenyl-s-triazines as UV stabilisers CIBA-GEIGY AG (CH) 1996-11-20 EP disclosed
EP-0654469-A1 O-Hydroxyphenyl-s-triazines as stabilisers for polymers CIBA-GEIGY AG (CH) 1995-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170189277-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF TYR, RAB5IF, MITF LMNA 814/4885ALDH1A1 1269/4885TSHR 3682/4885
US-20130259912-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF TYR, MITF, PUF60 LMNA 795/4885ALDH1A1 831/4885TSHR 4309/4885
US-20150157539-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES MITF, RAB5IF, TYR LMNA 683/4885ALDH1A1 281/4885TSHR 1743/4885
US-20130309285-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF TYR, RAB5IF, MITF LMNA 814/4885ALDH1A1 1269/4885TSHR 3682/4885
US-20150190320-A1 COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES XPA, ERCC1, ERCC4 LMNA 942/4885ALDH1A1 331/4885TSHR 2451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.