Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101807 | 0.81 | ALOX5 (0.57) | RAB9AKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9808697 | 0.76 | HPGD (0.59) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL19734616 | 0.75 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL14168120 | 0.75 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL6373010 | 0.74 | HPGD (0.56) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL7962444 | 0.74 | HPGD (0.56) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL7962440 | 0.74 | HPGD (0.56) | NPC1RAB9AMEN1KMT2APKM | |
| SCHEMBL12738664 | 0.74 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL7048118 | 0.73 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL2989926 | 0.73 | KMT2A (0.62) | NPC1RAB9AMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |