Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.37 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.37 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.37 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.37 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.37 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.37 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098016 | 1.00 | TAS1R3 (0.39) | TAS1R3TAS1R1NPSR1MEN1KMT2A | |
| SCHEMBL7099513 | 0.91 | ITGB1 (0.47) | MEN1KMT2AMAPTITGB1ITGA4 | |
| SCHEMBL7099510 | 0.91 | ITGB1 (0.47) | MEN1KMT2AMAPTITGB1ITGA4 | |
| SCHEMBL7098708 | 0.90 | MEN1 (0.45) | TAS1R3TAS1R1NPSR1MEN1KMT2A | |
| SCHEMBL7098706 | 0.90 | MEN1 (0.45) | TAS1R3TAS1R1NPSR1MEN1KMT2A | |
| SCHEMBL7105442 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7105443 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL7098745 | 0.87 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7247044 | 0.87 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL7247043 | 0.87 | ITGB1 (0.49) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | TANABE SEIYAKU CO., LTD. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130349-A1 | Inhibitors of alpha 4beta1 mediated cell adhesion | VCAM1, ICAM1, ITGB1 | TAS1R3 1381/4885TAS1R1 411/4885NPSR1 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.