Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 16/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090136 | 0.92 | NR1H2 (0.42) | NOTUMMAOACYP19A1NR1H2 | |
| SCHEMBL3863178 | 0.92 | NR1H2 (0.42) | NOTUMMAOACYP19A1NR1H2 | |
| SCHEMBL2854803 | 0.85 | NOTUM (0.42) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL7098110 | 0.80 | NFE2L2 (0.37) | NOTUMKEAP1CYP19A1NR1H2 | |
| SCHEMBL31245628 | 0.74 | IDO1 (0.47) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL170100 | 0.74 | IDO1 (0.47) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL241942 | 0.74 | NOTUM (0.50) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL20605667 | 0.74 | NOTUM (0.50) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL29842592 | 0.74 | NOTUM (0.59) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL454021 | 0.74 | GAA (0.47) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047729-B1 | COMPOSITION FOR BLEACHING MECHANICAL PULP | DE DONATO FAUSTO (IT) | 2003-01-08 | — | — | EP | claimed |
| EP-1047729-B1 | COMPOSITION FOR BLEACHING MECHANICAL PULP | DE DONATO FAUSTO (IT) | 2003-01-08 | — | — | EP | disclosed |
| EP-1047729-A1 | COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION | De Donato, Fausto (IT) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999029779-A1 | COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION | DONATO FAUSTO DE (IT) | 1999-06-17 | — | — | WO | disclosed |