SCHEMBL7098828

SCHEMBL7098828

O=S(=O)(O)CNc1cc2c(O)cc(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.48
CASP6 P55212 5/20 0.45
NSD2 O96028 3/20 0.45
DUSP3 P51452 2/20 0.45
PTPN5 P54829 2/20 0.45
PTPN11 Q06124 2/20 0.45
CASP7 P55210 1/20 0.45
PRMT1 Q99873 2/20 0.45
CTDSP1 Q9GZU7 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
APEX1 P27695 1/20 0.35
CYP1A2 P05177 3/20 0.35
MAPK1 P28482 1/20 0.35
DNASE1L3 Q13609 1/20 0.35
MEN1 O00255 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9095610 0.83 NT5E (0.45) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL10885566 0.82 NSD2 (0.44) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4392142 0.81 NSD2 (0.51) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL10897761 0.80 PRMT1 (0.61) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4436179 0.79 CASP6 (0.63) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1802332 0.78 CASP6 (0.56) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1373255 0.77 PRMT1 (0.65) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL7798817 0.77 NT5E (0.60) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL31635711 0.77 NT5E (0.60) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4650426 0.77 CA2 (0.35) CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062279-B1 REACTIVE DYES WITH A COMBINATION ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-09-10 EP disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
EP-0929610-B1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-08-28 EP disclosed
US-6197941-B1 TRIAZINE, METALLIZED, AZO, ANTHRAQUINONE, FORMAZAN, PHTHALOCYANINE, AND DIOXAZINE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed