Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 8/20 | 0.39 |
| ▸ | JAK2 | O60674 | 7/20 | 0.38 |
| ▸ | JAK1 | P23458 | 7/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846977 | 0.78 | POLB (0.50) | — | |
| SCHEMBL6846975 | 0.78 | POLB (0.50) | — | |
| SCHEMBL7094424 | 0.76 | MTNR1A (0.49) | SMYD3BTKADRA1A | |
| SCHEMBL6850768 | 0.74 | MEN1 (0.44) | ADRA1A | |
| SCHEMBL6850893 | 0.74 | KMT2A (0.49) | — | |
| SCHEMBL6849668 | 0.73 | HPGD (0.51) | — | |
| SCHEMBL6851228 | 0.72 | EPHX1 (0.44) | — | |
| SCHEMBL13531413 | 0.71 | HTR3A (0.42) | ADRA1A | |
| SCHEMBL13531389 | 0.71 | HTR3A (0.42) | ADRA1A | |
| SCHEMBL9617115 | 0.70 | EPHX2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |