Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333785 | 0.82 | MMP8 (0.47) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL9617114 | 0.81 | POLB (0.52) | MEN1ALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL7333796 | 0.76 | ADRA1A (0.47) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL7011484 | 0.74 | NPC1 (0.50) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL15624827 | 0.73 | NPC1 (0.76) | EPHX2NPC1RAB9AEPHX1CYP3A4 | |
| SCHEMBL2751488 | 0.73 | NPC1 (0.97) | EPHX2NPC1RAB9AEPHX1MEN1 | |
| SCHEMBL14984059 | 0.72 | NPC1 (0.74) | EPHX2NPC1RAB9AEPHX1CYP3A4 | |
| SCHEMBL12196154 | 0.72 | NPC1 (1.00) | EPHX2NPC1RAB9AEPHX1MEN1 | |
| SCHEMBL6849595 | 0.71 | MAPT (0.46) | EPHX2NPC1RAB9ACYP3A4MEN1 | |
| SCHEMBL6851396 | 0.71 | MCHR1 (0.46) | EPHX2NPC1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4013666-A | — | — | None | — | — | JP | disclosed |
| JP-H0413666-A | 1-(ALKOXYPHENYL)-3-(4,5,6,7-TETRAHYDROBENZIMIDAZOLYL)UREA | YAMANOUCHI PHARMACEUT CO LTD | 1992-01-17 | — | — | JP | disclosed |