SCHEMBL709977

SCHEMBL709977

C=CC1CC(C=C)CC(C=C)CC(C=C)C1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713535 1.00 ALDH1A1 (0.36) ALDH1A1ALOX15TDP1
SCHEMBL17798828 1.00
SCHEMBL215376 1.00 ALDH1A1 (0.36) ALDH1A1ALOX15TDP1
SCHEMBL7990081 0.84
SCHEMBL815359 0.84
SCHEMBL7972784 0.84
SCHEMBL7972779 0.84
SCHEMBL5147176 0.81 ALDH1A1 (0.32) ALDH1A1ALOX15
SCHEMBL9007532 0.78
SCHEMBL24185921 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2342263-B1 CROSSLINKED POLYSULFIDE-CONTAINING CYCLOALIPHATIC COMPOUND MOMENTIVE PERFORMANCE MAT INC (US) 2016-06-22 EP disclosed
US-8846170-B2 Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2014-09-30 US disclosed
EP-2349992-B1 THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2014-08-27 EP disclosed
US-8470197-B2 Crosslinked polysulfide-containing cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-06-25 US disclosed
EP-2342275-B1 SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2013-05-01 EP disclosed
EP-2342274-B1 SULFUR-CONTAINING CYCLOALI PHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2013-04-17 EP disclosed
US-8334340-B2 Sulfur-containing cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2012-12-18 US disclosed
US-20120116002-A1 SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SULFUR-CONTAINING CYCLOALIPHATIC COMPOUND AND ARTICLES FABRICATED THEREFROM MOMENTIVE PERFORMANCE MATERICALS INC. (US) 2012-05-10 US disclosed
US-8124206-B2 Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2012-02-28 US disclosed
EP-2349992-A1 THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM Momentive Performance Materials Inc. (US) 2011-08-03 EP disclosed
WO-2010051396-A1 THIOCARBAMOYLDISULFANYL-FUNCTIONAL CYCLOALIPHATIC COMPOUND, PROCESS FOR ITS PREPARATION, FILLED SULFUR-VULCANIZABLE ELASTOMER COMPOSITION CONTAINING SAME AND ARTICLES FABRICATED THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-05-06 WO disclosed
US-20100112259-A1 Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2010-05-06 US disclosed
US-20100112258-A1 Crosslinked polysulfide-containing cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2010-05-06 US disclosed
US-7674861-B1 Thiocarbamoyldisufanyl-functional cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-03-09 US disclosed
EP-0786463-B1 Crosslinkable compositions WACKER CHEMIE GMBH (DE) 2003-05-21 EP disclosed
US-6093782-A MIXTURE COMPRISING AN ORGANOSILICON COMPOUND HAVING VINYL MOIETIES AND AN ORGANOSILICON COMPOUND HAVING SILICON-HYDROGEN MOIETIES, HYDROSILATION CATALYST, ROOM TEMPERATURE CROSSLINKING INHIBITOR; RELEASE AGENTS WACKER-CHEMIE GMBH (DE) 2000-07-25 US disclosed
EP-0924275-B1 Compositions containing addition reaction-curable organosilicon compounds WACKER CHEMIE GMBH (DE) 2000-04-26 EP disclosed
EP-0924275-A1 Compositions containing addition reaction-curable organosilicon compounds Wacker-Chemie GmbH (DE) 1999-06-23 EP disclosed
US-5691435-A ORGANOSILICON COMPOUNDS WITH SILICON-BONDED HYDROGEN WACKER-CHEMIE GMBH (DE) 1997-11-25 US disclosed
EP-0786463-A1 Crosslinkable compositions Wacker-Chemie GmbH (DE) 1997-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112258-A1 Crosslinked polysulfide-containing cycloaliphatic compound, process for its preparation, filled sulfur-vulcanizable elastomer composition containing same and articles fabricated therefrom CRHR2, H1-2, GRIN2D ALDH1A1 4622/4885ALOX15 1663/4885TDP1 4282/4885
US-20100112259-A1 Sulfur-containing cycloaliphatic compound, filled sulfur-vulcanizable elastomer composition containing sulfur-containing cycloaliphatic compound and articles fabricated therefrom CRHR2, CRH, CRHR1 ALDH1A1 4813/4885ALOX15 343/4885TDP1 4814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.