SCHEMBL7100097

SCHEMBL7100097

c1cc(-c2ccc3[nH]nnc3n2)no1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7100549 0.71 CCNC (0.32)
SCHEMBL5798894 0.70 MDM2 (0.36) NPC1RAB9A
SCHEMBL3082762 0.68 NPC1 (0.42) CHRM1NPC1RAB9A
SCHEMBL1421802 0.65 NOS1 (0.35)
SCHEMBL1673907 0.65 SIRT2 (0.38)
SCHEMBL9996915 0.65 GAA (0.41) RAB9A
SCHEMBL17326272 0.65 TRPA1 (0.33)
SCHEMBL27647008 0.63 CYP1A2 (0.35) CHRM1NPC1RAB9A
SCHEMBL6202767 0.63 MDM2 (0.43) NPC1RAB9A
SCHEMBL2457606 0.62 GSK3B (0.58) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101981160-A Sulfoxidation catalysts and methods and systems using the same AUTERRA INC 2011-02-23 CN disclosed
EP-1370559-A1 TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS Pfizer Products Inc. (US) 2003-12-17 EP disclosed
WO-2002072579-A1 TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS PFIZER PRODUCTS INC. (US) 2002-09-19 WO disclosed