Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30369056 | 0.72 | PIK3CD (0.36) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL7100097 | 0.71 | CHRM1 (0.30) | — | |
| SCHEMBL5799482 | 0.70 | HPGDS (0.40) | HPGDSLTA4H | |
| SCHEMBL27763441 | 0.69 | ALDH1A1 (0.42) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL315001 | 0.68 | HPGDS (0.44) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL912864 | 0.65 | LTA4H (0.37) | HPGDSLTA4H | |
| SCHEMBL27176347 | 0.65 | HPGDS (0.38) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL30066176 | 0.65 | HPGDS (0.38) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL28714481 | 0.65 | HPGDS (0.39) | CCNCCDK8HPGDSLTA4H | |
| SCHEMBL20571906 | 0.64 | CCNC (0.33) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370559-A1 | TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS | Pfizer Products Inc. (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002072579-A1 | TRIAZOLOPYRIDINES AS ANTI-INFLAMMATORY AGENTS | PFIZER PRODUCTS INC. (US) | 2002-09-19 | — | — | WO | disclosed |