Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPGS | Q05932 | 2/20 | 1.00 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.89 |
| ▸ | GART | P22102 | 5/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.60 |
| ▸ | ATIC | P31939 | 2/20 | 0.58 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.56 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofolate SCHEMBL1069545 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL4535491 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL29870853 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL159231 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL8030 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL2691812 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL29435894 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL30051444 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL9879710 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL258530 | 0.94 | SOST (1.00) | FPGSSOSTGARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097858-A1 | IDENTIFICATION METHOD FOR PROTECTING PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-11-27 | — | — | WO | disclosed |
| EP-0348641-B1 | Process for the preparation of tetrahydrofolates | EPROVA AG (CH) | 1995-06-21 | — | — | EP | disclosed |