SCHEMBL7100203

SCHEMBL7100203

Cc1ccc(S(=O)(=O)NF)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
MMP1 P03956 1/20 0.61
MMP2 P08253 1/20 0.61
MMP9 P14780 1/20 0.61
MMP8 P22894 1/20 0.61
MMP13 P45452 1/20 0.61
ALDH1A1 P00352 7/20 0.57
KDM4E B2RXH2 3/20 0.55
HPGD P15428 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
CYP2C9 P11712 3/20 0.55
CYP2C19 P33261 3/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP2D6 P10635 2/20 0.55
MAPT P10636 2/20 0.55
ALOX12 P18054 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541544 0.82 PTGS2 (0.66) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL9246895 0.81 ENPP2 (0.50) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL7627224 0.80 ALDH1A1 (0.72) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL187561 0.80 GAA (0.70) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL3818860 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL30960 0.78 GAA (1.00) GAASMN1; SMN2CA1CA2MMP1
Potassium SCHEMBL29525387 0.78 GAA (0.67) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL15301365 0.78 GAA (0.67) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL10950543 0.78 GAA (0.67) GAASMN1; SMN2CA1CA2MMP1
SCHEMBL16509308 0.78 GAA (0.67) GAASMN1; SMN2CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5403957-A Method for preparing N-fluorosulfonimides ALLIEDSIGNAL INC. 1995-04-04 US claimed
EP-2913329-A1 METHOD FOR MANUFACTURING DIFLUORO ESTER COMPOUND Asahi Glass Company, Limited (JP) 2015-09-02 EP disclosed
US-20150175632-A1 METHOD FOR PRODUCING DIFLUORO ESTER COMPOUND ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-25 US disclosed
EP-0789022-B1 Difluoroprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS CO LTD (JP) 2003-06-18 EP disclosed
US-6184340-B1 TREATING WITH AQUEOUS ALKALINE TREATMENT OR WITH ALKALINE OXIDANT FOR THE PURPOSE OF RENDERING THE PATHOGENS HARMLESS AND DISSOLVING THE POLYVINYLALCOHOL NON-WOVEN FOR DISPOSAL PURPOSES. ECOLAB INC. 2001-02-06 US disclosed
EP-0669329-B1 Difluorprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS CO LTD (JP) 1998-05-20 EP disclosed
US-5747531-A STABILITY; ANTICOAGULANTS, VASODILATORS ASAHI GLASS COMPANY LTD. (JP) 1998-05-05 US disclosed
EP-0789022-A1 Difluoroprostacyclins, intermediates for production thereof and process for production ASAHI GLASS COMPANY LTD. (JP) 1997-08-13 EP disclosed
US-5616732-A Intermediates for difluoroprostacyclins and methods for their production ASAHI GLASS COMPANY LTD. (JP) 1997-04-01 US disclosed
EP-0665831-B1 AN IMPROVED METHOD FOR PREPARING N-FLUOROSULFONIMIDES ALLIED SIGNAL INC (US) 1997-03-19 EP disclosed
US-5538995-A Difluoroprostacyclins ASAHI GLASS COMPANY LTD. (JP) 1996-07-23 US disclosed
WO-1996008502-A1 PREPARATION OF (8S)-8-FLUOROERYTHROMYCINS WITH N-F FLUORINATING AGENTS ALLIEDSIGNAL INC. (US) 1996-03-21 WO disclosed
US-5478964-A N-fluorosulfonimides and their application as fluorinating agents ALLIED-SIGNAL INC. (US) 1995-12-26 US disclosed
EP-0669329-A1 Difluorprostacyclins, intermediates for production thereof and processes for production thereof ASAHI GLASS COMPANY LTD. (JP) 1995-08-30 EP disclosed
EP-0665831-A1 AN IMPROVED METHOD FOR PREPARING N-FLUOROSULFONIMIDES. ALLIED SIGNAL INC (US) 1995-08-09 EP disclosed
US-5403957-A Method for preparing N-fluorosulfonimides ALLIEDSIGNAL INC. 1995-04-04 US disclosed
WO-1994008955-A1 AN IMPROVED METHOD FOR PREPARING N-FLUOROSULFONIMIDES ALLIED-SIGNAL INC. (US) 1994-04-28 WO disclosed
US-5254732-A N-fluorosulfonimides and their application as fluorinating agents ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150175632-A1 METHOD FOR PRODUCING DIFLUORO ESTER COMPOUND CYP2F1, AFF1, FLI1 GAA 1608/4885SMN1; SMN2 2766/4885CA1 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.