Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289097 | 0.79 | CA2 (0.43) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL6163795 | 0.77 | ENPP2 (0.46) | ENPP2ALDH1A1GSK3BTSHRMAPT | |
| SCHEMBL27520915 | 0.76 | CYP19A1 (0.48) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL691258 | 0.75 | CA2 (0.52) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL3696286 | 0.75 | CA2 (0.52) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL26162676 | 0.75 | CA2 (0.52) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL2964706 | 0.75 | HRH3 (0.43) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL31192685 | 0.74 | MAP2K1 (0.33) | ENPP2CA2CA12CA3CA6 | |
| SCHEMBL387119 | 0.73 | ESR1 (0.44) | CA2CA12CA3CA9CA14 | |
| SCHEMBL28387350 | 0.72 | CA12 (0.41) | CA2CA12CA3CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666925-B | Method for synthesizing isoindolo [2,1-b ] isoquinoline-5 (7H) -ketone compound | 广州大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-113666925-A | Method for synthesizing isoindolo [2,1-b ] isoquinoline-5 (7H) -ketone compound | 广州大学 | 2021-11-19 | — | — | CN | disclosed |
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | ENPP2 455/4885CA2 1203/4885CA12 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.