Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28655800 | 0.98 | TP53 (0.41) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL28327731 | 0.96 | TP53 (0.39) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL9392661 | 0.81 | TP53 (0.41) | TP53FDPSCA2MAPK1GPR84 | |
| SCHEMBL1138500 | 0.78 | TP53 (0.42) | TP53FDPSCA2MAPK1GPR84 | |
| SCHEMBL7103231 | 0.77 | TP53 (0.32) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL31544523 | 0.76 | ALDH1A1 (0.44) | TP53RECQLFDPSCA2MAPK1 | |
| SCHEMBL7100480 | 0.75 | CA2 (0.35) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL125029 | 0.75 | ALDH1A1 (0.50) | TP53RECQLCA2MAPK1CA1 | |
| SCHEMBL10923556 | 0.75 | TP53 (0.35) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL15754300 | 0.75 | TP53 (0.48) | TP53FDPSGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6572839-B2 | Xanthene dye structure with a hydrophilic and lipophilic group bound to the same carbon, ultrasonic | HITACHI, LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20010041163-A1 | Sensitizer for tumor treatment | HITACHI, LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041163-A1 | Sensitizer for tumor treatment | HNRNPR, HNRNPUL1, SON | TP53 12/4885LCK 4714/4885PPARD 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.