Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720701 | 0.86 | CA12 (0.34) | CA2 | |
| SCHEMBL28655800 | 0.78 | TP53 (0.41) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10923556 | 0.77 | TP53 (0.35) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7100480 | 0.77 | CA2 (0.35) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL28327731 | 0.77 | TP53 (0.39) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL7100482 | 0.77 | TP53 (0.39) | TP53LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL23181465 | 0.76 | TP53 (0.38) | TP53TSHRSMN1; SMN2FDPSDNM1 | |
| SCHEMBL7101329 | 0.76 | TP53 (0.38) | TP53TSHRSMN1; SMN2FDPSDNM1 | |
| SCHEMBL11250128 | 0.74 | ALDH1A1 (0.46) | TSHRSMN1; SMN2CYP3A4L3MBTL1CA2 | |
| SCHEMBL1415215 | 0.73 | TP53 (0.34) | TP53LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |