Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 11/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6700005 | 0.98 | GBA1 (0.51) | GBA1GAAMAPTKDM4EGFER | |
| Hydrochloric Acid SCHEMBL6703140 | 0.98 | GBA1 (0.51) | GBA1GAAMAPTKDM4EGFER | |
| SCHEMBL7039463 | 0.77 | GBA1 (0.39) | GBA1GAAMAPTKDM4EGFER | |
| SCHEMBL6696588 | 0.77 | GBA1 (0.57) | GBA1MAPTSMN1; SMN2SLC18A3ALDH1A1 | |
| SCHEMBL3337833 | 0.77 | GBA1 (0.57) | GBA1MAPTSMN1; SMN2SLC18A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6698454 | 0.72 | GFER (0.38) | GBA1GAAMAPTKDM4EGFER | |
| SCHEMBL4890984 | 0.71 | FFAR1 (0.43) | GAAMAPTKDM4ETHRBALDH1A1 | |
| SCHEMBL78460 | 0.71 | FFAR1 (0.43) | GAAMAPTKDM4ETHRBALDH1A1 | |
| SCHEMBL78175 | 0.70 | ALDH1A1 (0.42) | GBA1GAAMAPTKDM4EGFER | |
| SCHEMBL4675876 | 0.70 | GBA1 (0.37) | GBA1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341508-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045669-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |