Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | PDE4A | P27815 | 4/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100037 | 0.90 | ADORA2B (0.54) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7099928 | 0.87 | ADORA2B (0.50) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL7100345 | 0.76 | ADORA2B (0.50) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| Phosphoric Acid SCHEMBL8861529 | 0.75 | PDE4A (0.68) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL316911 | 0.71 | PDE4A (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| Fluoride SCHEMBL30358487 | 0.70 | ADORA2A (0.85) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL13189695 | 0.70 | ADORA2B (0.50) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL515931 | 0.70 | ADORA2A (0.68) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL21381243 | 0.69 | PDE4A (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL21381247 | 0.69 | PDE4A (1.00) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| CN-1331695-A | Organic phosphorus compounds and their use | JOMAA PHARMACEUTICAL GMBH (DE) | 2002-01-16 | — | — | CN | disclosed |