Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.54 |
| ▸ | PDE4A | P27815 | 4/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100798 | 0.90 | ADORA2B (0.55) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7100345 | 0.86 | ADORA2B (0.50) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7099928 | 0.78 | ADORA2B (0.50) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Bisdionin B SCHEMBL29896692 | 0.71 | ADORA2B (0.74) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22471389 | 0.70 | ADORA2B (0.63) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL316911 | 0.70 | PDE4A (1.00) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Bisdionin D SCHEMBL16120988 | 0.69 | ADORA2B (0.79) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Bisdionin C SCHEMBL10018600 | 0.69 | CHIT1 (0.75) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6892168 | 0.69 | ADORA2B (0.65) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| Phosphoric Acid SCHEMBL8861529 | 0.69 | PDE4A (0.68) | ADORA2BPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140952-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | Jomaa Pharmaka GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037477-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | JOMAA PHARMAKA GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |