Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935943 | 0.92 | ESR1 (0.54) | ESR1ESR2CYP3A4ALDH1A1AR | |
| SCHEMBL7972245 | 0.88 | ESR1 (0.54) | ESR1ESR2CYP3A4ALDH1A1HPGD | |
| SCHEMBL5995899 | 0.87 | ESR1 (0.52) | ESR1ESR2CYP3A4ALDH1A1HPGD | |
| SCHEMBL730689 | 0.85 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1HPGD | |
| SCHEMBL21048974 | 0.85 | ESR1 (0.47) | ESR1ESR2CYP3A4ALDH1A1HPGD | |
| SCHEMBL11726495 | 0.84 | SHBG (0.56) | ESR1ESR2CYP3A4ALDH1A1HPGD | |
| SCHEMBL3691307 | 0.84 | PTGS1 (0.46) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL5873699 | 0.83 | ESR1 (0.57) | ESR1ESR2AR | |
| SCHEMBL7969173 | 0.83 | ESR1 (0.61) | ESR1ESR2CYP3A4ALDH1A1AR | |
| SCHEMBL8410509 | 0.83 | ESR1 (0.42) | ESR1ESR2CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242501-B1 | POLYETHER CARBONATES | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1242501-A1 | POLYETHER CARBONATES | Bayer Aktiengesellschaft (DE) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044346-A1 | POLYETHER CARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-21 | — | — | WO | disclosed |
| US-5621031-A | Sheathing material for optical fibers, based on polyalkylene terephthalate/polycarbonate | BAYER AG (DE) | 1997-04-15 | — | — | US | disclosed |
| US-4973652-A | Process for the production of aromatic polycarbonates, aromatic polyester carbonates and aromatic polyesters with p containing catalyst and mixture of hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |